Author(s): Dalamagka M , Dimaki P, Tsetsou A, Boga F
Numerous studies have demonstrated that the drugs currently used for sedation are associated with adverse events, particularly when combined with opiates. Regardless of the agent or agents used, it is important to monitor the depth of sedation, allowing a rational “targeted sedation practice. Titration and interruption of sedative infusions may be an important tool to maintain patients within a predefined target sedation range. Dexmedetomidine, when compared to conventional sedatives and opiates, has been demonstrated to be associated with both sedative and analgesic sparing effects, reduced delirium and agitation, minimal respiratory depression and predictable and desirable cardiovascular effects