Transcranial magnetic stimulation (TMS) is a noninvasive method for treating neurological disorders. The aim of this study is to identify any change in the brain state in migraine patients after Pico-Tesla (pT)-TMS application. Magneto encephalographic (MEG) recordings of 30 Migraine patients were obtained using a whole-head 122 - channel MEG system in a magnetically shielded room of low magnetic noise. The subjects were 12 male and 18 female volunteers between 45-67 years of age. A double-blind experimental design was used in order to look for possible effects of external Pico - Tesla TMS on migraine patients. The results were statistically significant at 22 out of 30 patients (73.3%). We observe that 8 out of 30 patients (26.7%) had partial improvement whereas 22 out of 30 patients (73.3 %) had improvement to pT-TMS. From our study population 12 out of 18 women (66.7%) and 10 out to 12 men (83.3%) had improvement to pT-TMS. The pT-TMS has the potential to be an important non invasive safe and efficacious modality in the management of idiopathic migraine patients.
Author(s): Photios Anninos, Adam Adamopoulos, Nicolaos Tsagas, and Athanasia Kotini