Enliven: Journal of Anesthesiology and Critical Care Medicine | Open Access Journals | Open Access Articles
Author Year of publication No. patients Characteristics of the study population Treatment and results

Plouin et al.[24]

1998

49

Hypertension and unilateral RAS

Balloon angioplasty (with or without stent placement): No significant change in SBP or DBP No significant change in SCr

Webster et al. [25]

1998

55

Resistant hypertension and bilateral or unilateral RAS

Balloon angioplasty:
1) Bilateral RAS:
Significant improvement in SBP after angioplasty
No significant change in DBP
No significant change in SCr
2) Unilateral RAS:
No significant change in SBP and DBP
No significant change in SCr 1998

Van Jaarsveld et al. [26]

2000

106

Resistant hypertension with normal or mild chronic renal insufficiency and RAS

Balloon angioplasty:
No significant change in SBP or DBP
No significant change in SCr

Bax et al. [27]

2009

140

Chronic renal insufficiency and ostial RAS

Renal artery stenting:
No significant effect on progression of renal dysfunction
No significant effect on BP

ASTRAL investigators [28]

2009

806

Resistant hypertension or unexplained chronic renal insufficiency and RAS

Renal artery stenting:
No significant effect on renal function
No significant effect on BP
No significant effect on mortality

Scarpioni et al. [29]

2009*

52

Resistant hypertension with chronic renal insufficiency and RAS

Renal artery stenting:
No significant effect on renal function
No significant effect on BP
No significant effect on mortality

Cooper et al. [18]

2014

947

Hypertension or chronic kidney disease and RAS,

Renal artery stenting:
No significant benefit in the prevention of clinical events
No significant difference in all causes mortality
Modest reduction of BP


BP: blood pressure; DBP: diastolic blood pressure; RAS: renal artery stenosis; SBP: systolic blood pressure; SCr: serum creatinine. *Presented


Table 1. Randomized trials comparing to medical therapy for renal artery stenosis.