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CONTINUOUS VARIABLES

SUCCESS (N=34)

FAILURE (N=8)

p*

Mean; (SD)

Mean; (SD)

AGE (years)

70.71; 70.50 (7.26)

72.75; 72.50 (6.65)

0.413

PaO2 START (mmHg)

57.00; 54.50 (18.17)

61.13; 64.00 (10.01)

0.290

PaCO2 START (mmHg)

93.29; 92.00 (14.13)

94.25; 97.50 (14.81)

0.724

pH START

7.23; 7.23 (0.012)

7.24; 7.24 (0.012)

0.079

RR START (breaths/min)

24.00; 25.00 (9.43)

23.38; 27.00 (8.88)

0.797

GCS

12.76; 13.00 (2.13)

11.38; 12.50 (3.50)

0.362

APACHE II

20.71; 20.00 (4.66)

22.50; 22.00 (5.78)

0.500

PaO2 NIV (mmHg)

68.91; 65.50 (13.91)

67.25; 66.00 (6.02)

0.936

PaCO2 NIV (mmHg)

78.91; 76.50 (14.16)

83.63; 85.50 (12.42)

0.344

pH NIV

7.32; 7.32 (0.047)

7.29; 7.29 (0.053)

0.187

LENGHT OF STAY (days)

12.50; 9.00 (8.28)

11.25; 8.00 (10.37)

0.395

?pH (NIV-START)

0.09; 0.09 (0.05)

0.056; 0.06 (0.05)

0.107

?PaO2 (NIV-START) (mmHg)

11.91; 12.00 (18.13)

6.12; 3.5 (13.92)

0.336

?PaCO2 (START-NIV) (mmHg)

14.38; 14.00 (9.85)

10.62: 12.50 (11.20)

0.451

CATEGORICAL VARIABLES

SUCCESS

FAILURE

p*

OR

95% CI

GENDER

M (21)

16 (47.1%)

5 (62.5%)

0.432

1

0.11-2.59

F (21)

18 (52.9%)

3 (37.5%)

0.533

DICHOTOMIZED pH START

< 0.1 (24)

17 (50%)

7 (87.5%)

0.054

0.143

0.016-1.290

= 0.1 (18)

17 (50%)

1 (12.5%)

1

Table 3. Analysis of the association of the evaluated variables with the outcome: univariable analysis (subgroup analysis of patients with pH START > 7.20 and = 7.25, n= 42).


PaO2: partial pressure of arterial oxigen; PaCO2: partial pressure of arterial carbon dioxide; RR: respiratory rate; GCS: Glasgow Coma Scale; APACHE II: Acute Physiology and Chronic Health Evaluation II; NIV: Non invasive ventilation; PaO2, PaCO2, pH, RR START: values measured at admission; PaO2, PaCO2, pH NIV: values measured after 2 – 4 hours of NIV; ?pH, ?PaO2, ?PaCO2: variations of pH, PaO2, and PaCO2 after 2-4 hours of treatment.


SD: Standard Deviation; *Mann-Whitney test; ** Chi-square test; OR: Odds ratio; 95% CI: 95% confidence interval.