Enliven: Journal of Anesthesiology and Critical Care Medicine | Open Access Journals | Open Access Articles

CONTINUOUS VARIABLES

SUCCESS (N=151)

FAILURE (N=50)

p

Mean; (SD)

Mean; (SD)

AGE (years)

70.99; (8.74)

73.56; (8.35)

0.058°

PaO2 START (mmHg)

57.48; (17.26)

55.62; (17.38)

0.392°

PaCO2 START (mmHg)

93.10; (15.08)

98.45; (16.09)

0.029°

pH START

7.26; (0.06)

7.23; (0.08)

0.033°

RR START (breaths/min)

24.76; (7.55)

25.42; (9.28)

0.237°

GCS

12.94; (2.44)

11.24; (3.32)

0.001°°

APACHE II

20.02; (4.81)

24.84; (6.35)

< 0.001°

PaO2 NIV (mmHg)

66.96; (12.03)

70.62; (15.31)

0.235°

PaCO2 NIV (mmHg)

77.62; (13.62)

82.12; (15.24)

0.044°

pH NIV

7.34; (0.06)

7.32; (0.08)

0.060°

LENGHT OF STAY (days)

12.14; (7.67)

15.60; (18.30)

0.528°

PaO2 END (mmHg)

67.21; (9.48)

66.66; (16.08)

0.187°

PaCO2 END (mmHg)

62.40; (8.33)

94.68; (28.50)

< 0.001°

pH END

7.39; (0.04)

7.28; (0.10)

< 0.001°

?pH (NIV-START)

0.08; (0.05)

0.09; (0.07)

0.266°°°

?PaO2 (NIV-START) (mmHg)

9.48; (17.26)

15; (22.32)

0.071°°

?PaCO2 (START-NIV) (mmHg)

15.48; (12.09)

16.33; (14.27)

0.682°°

CATEGORICAL VARIABLES

SUCCESS

FAILURE

p*

OR

95% CI

GENDER

M (107)

77 (51%)

30 (60%)

0.269

1

0.36-1.33

F (94)

74 (49%)

20 (40%)

0.69

DICHOTOMIZED pH START

= 7.25 (83)

58 (38%)

25 (50%)

0.149

1.60

0.84-3.05

> 7.25 (118)

93 (61.6%)

25 (50%)

1

DICHOTOMIZED pH START

= 7.20 (41))

24 (15.9%)

17 (34%)

0.006

1

0.18-0.76

> 7.20 (160)

127 (84.1%)

33 (66%)

0.37


Table 2. Analysis of the association of the evaluated variables with the outcome: univariable analysis (entire cohort, n= 201). PaO2: partial pressure of arterial oxygen; PaCO2: partial pressure of arterial carbon dioxide; RR: respiratory rate; GCS: Glasgow Coma Scale; APACHE II: Acute Physiology and Chronic Health Evaluation II; NIV: Non invasive ventilation; PaO2, PaCO2, pH, RR START: values measured at admission; PaO2, PaCO2, pH NIV: values measured after 2 – 4 hours of NIV; PaO2, PaCO2, pH END: values measured at discharge/death/ETI; ?pH, ?PaO2, ?PaCO2: variations of pH, PaO2, and PaCO2 after 2-4 hours of treatment. SD: Standard Deviation; ° Mann-Whitney test; °° t-test ; °°° Unequal variance t-test; * Chi-square test; OR: Odds ratio; 95% CI: 95% confidence interval.