Background:
Few studies have reported rates of adverse drug reactions (ADRs) within low-income countries, and the resulting rates are extremely variable. Limited information exists about patterns of ADRs within African countries.
Objective:
To identify the incidence and describe the types of ADRs for adult admissions to the Kamuzu Central Hospital in Lilongwe, Malawi.
Methods:
In this retrospective chart review, baseline descriptive information for all patients and details surrounding any identified potential ADR were documented. Only medical charts that included both laboratory results and a medication administration record were included. An expert panel reviewed all potential ADRs for study inclusion.
Results:
263 charts were reviewed and only 16% (42) met inclusion criteria. Of those 42 charts, 4 ADRs were identified. A cumulative ADR occurrence of 9.5% was observed.
Conclusions:
The preliminary incidence of ADRs in Malawi appears high and requires further evaluation to identify potential causes and solutions.
Author(s): Yardlee S. Kauffman, Sharon E. Connor, Lauren J. Jonkman, Tadala Himisi, Sandra L. Kane-Gill, E. Miranda Gillespie, and Gerald P. Douglas