The subject of phytochemistry has developed in recent years as a distinct discipline, somewhere in between natural product organic chemistry and plant biochemistry is closely related to both. Phytochemical and pharmacological screening of compounds of natural or synthetic has been the source of innumerable therapeutic agents. Plants are used in different countries as potent and powerful drugs. A wide range of medicinal plant parts is used for extract as raw drugs and they possess varied medicinal properties. The different pats used include seeds, root, stem, flower, fruit and leaves and modified plant organs.A systemic investigation was undertaken to screen the phytochemical and pharmacological activity of Firmianacolorata belonging to the family: Malvaceae.The leaves of F.colorata(Family: Malvaceae) were collected from Chittagong University. In the present study, ethanol, n-hexane and chloroform extractives ofFirmianacoloratawere screened for pharmacological and biological tests. It is observed that the ethanolic, chloroform and n-hexane extracts of F.coloratacontains glycosides, steroiods, alkaloids, saponins, reducing sugar, gums and amides.In this research work,the open field test after 120 minutes, square crossed by the control (42) and positive control group (16). Moreover, at the 500 mg/kg dose, Ethanol (30) and Chloroform (29) extract significantly decreases the movement then n-Hexane extract (34) shown in table 1. In the hole cross test after 120 minutes, the number of holes crossed by the control group (11) and positive control group (8). In this research work,the test samples of F.colorata at the dose of 400 mg/kg ethanol extract crossing movements of the experimental animals were almost similar to the control group (11). In this research work,chloroform (12) and n-hexane (13) extracts shows no activity in this method.
Author(s): Farhana Hoque, Md. Shahidul Islam