Author(s): Laura Kleinebrecht, Amin Polzin, Jan Balzer, Tienush Rassaf and Tobias Zeus
Patent foramen ovale (PFO) and atrial septal defect (ASD) are frequent congenital heart defects in adults. While the indication for surgical or interventional closure of an ASD is sufficiently evaluated, the necessity of closing a PFO remains a topic of academic discussions. In this article we present epidemiological data, show the actual anatomic classification, highlight relevant aspects of periinterventional imaging and review the latest trials. Moreover, we present the actual evidence relating to antiplatelet medication following device closure.