Multinodular goiter is the most common type of goiter in elderly and its incidence increases with age. The diagnostic evaluation relating to functional and morphological characterization has examined through serum TSH concentration and imaging. A statistical analysis called χ2 test has done in order to evaluate the sample of 126 patients pertaining to multi nodular goiter. Laboratory tests performed at Nuclear Medicine, Oncology and Radiotherapy Institute (NORI) Islamabad (Pakistan) have observed both hypothyroid and hyperthyroid patients with high and low TSH levels respectively. The data along with detailed history was collected with the help of clinicians in NORI and entered in the patient’s Performa (ANNEXUREII). TSH levels ranging from 0.27-4.2 μIU/ml was considered as normal for the diagnosis in thyroid function tests (TFTs). Statistically non-significant difference between hypothyroid and hyperthyroid patients of multi nodular goiter versus control group individuals was observed. The study has concluded that the prevalence of multi nodular goiter is not dependent on the higher and lower concentration of TSH.
Author(s): Muhammad Ameen