Enliven: Clinical Cardiology and Research

Gender-Related Differences in Risk Profile in Young Patients with St-Elevation Myocardial Infarction a 7-Year Single Centre Experience
Author(s): Chiara Lazzeri, MD, Marco Chiostri, MD, Maria Grazia D?Alfonso, MD, Alessio Mattesini, MD, Gian Franco Gensini, MD, and Serafina Valente, MD

Few studies have focused on acute ST-elevation myocardial infarction (STEMI) in young patients. We aimed to analyze the incidence, risk factors, management, and prognosis of STEMI in 182 consecutive young patients (age </= 50 years) (2004 to 2012), focusing on gender-related differences.

Males (87.4%) showed higher BMI values (p=0.004), a higher incidence of overweight and obesity (p=0.016). Diabetes was more frequent in females (p=0.02).

The main findings of your investigation are as follows: a) over the 7 year-study period the percentage of young STEMI patients did not change; b) the risk profile of males was different from that of females who showed a higher incidence of diabetes, while the frequency of smoking and hypertension was comparable between the two subgroups; c) no gender-related difference was detectable in management also in regard to medical therapy at discharge; d) young STEMI patients showed a good prognosis at short and long term.