In this study we have analyzed 100 people. 40 patients Autism disease and 60 persons control group.The gene polymorphisme 5-HTTLPR analyzed in terms of genetic mutations made. In this study, people who have genetic mutations were targeted, with nervous disorders, Autism disease. In fact, of all people with Autism disease. 40 patients Autism disease had a genetic mutations in the gene polymorphisme 5-HTTLPR Autism disease. Any genetic mutations in the target genes control group, did not show. The aim of this review is to summarize the key findings from genetic and epidemiological research, which show that autism is a complex disorder resulting from the combination of genetic and environmental factors. Remarkable advances in the knowledge of genetic causes of autism have resulted from the great efforts made in the field of genetics. The identification of specific alleles contributing to the autism spectrum has supplied important pieces for the autism puzzle. However, many questions remain unanswered, and new questions are raised by recent results. Moreover, given the amount of evidence supporting a significant contribution of environmental factors to autism risk, it is now clear that the search for environmental factors should be reinforced. One aspect of this search that has been neglected so far is the study of interactions between genes and environmental factors.
Author(s): Shahin Asadi*1, Mahsa Jamali2, Hamideh Mohammadzadeh2, Vida Vahdani Kia2, Rana Bagheri2 and Roya Pourjafar2