Enliven: Surgery and Transplantation

Advancements and Challenges in Islet Transplantation
Author(s): Joel Montane

Islet transplantation is an established therapeutic procedure in which islets isolated from pancreas of cadaveric organ donors are transplanted into the
portal vein of a subset of type 1 diabetic patients with complicated glycemic control. Over the last eight years, more than 850 islet transplants have
been performed in more than 30 international transplant centers according to the International Islet Transplant Registry. Islet transplantation is being
performed by normothermic perfusion, a minimally invasive procedure with fewer potential complications than full pancreas transplantation.